La liaison réversible NCO appliquée aux domaines de l'inhibition d'enzymes et des oligomères bio-mimétiques

La liaison réversible NCO appliquée aux domaines de l'inhibition d'enzymes et des oligomères bio-mimétiques

Cette thèse décrit le développement d’une gamme d’inhibiteurs de la protéase du VIH-1 et d’un oligomère bio-mimétique comportant en leur sein une ou plusieurs interactions réversibles entre une amine tertiaire et un carbonyle, appelée interaction NCO. Cette interaction est favorisée en milieu fortem...

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Bibliographic Details
Main Author:	Gros, Guillaume
Other Authors:	Lyon, École normale supérieure
Language:	fr
Published:	2015
Subjects:	Interaction amine tertiaire - carbonyle (NCO) Inhibiteur enzymatique VIH Amination réductrice Foldamère Oligomère Triazacyclononane Tertiary amine - carbonyl (NCO) interaction Enzymatic inhibitor HIV Reductive amination Foldamer Oligomer
Online Access:	http://www.theses.fr/2015ENSL0983/document

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