L'inhibition du récepteur nucléaire PPARB diminue la croissance et l'invasivité des cellules cancéreuses mammaires humaines

L'inhibition du récepteur nucléaire PPARB diminue la croissance et l'invasivité des cellules cancéreuses mammaires humaines

Les récepteurs nucléaires PPAR sont régulés par les acides gras polyinsaturés n-3 (AGPI n-3), dont l’acide docosahexaènoïque (DHA, 22:6n-3) qui inhibe la croissance des lignées de cellules cancéreuses mammaires. Des siRNA et des ligands pharmacologiques des PPAR (α, β et γ) ont permis de montrer que...

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Bibliographic Details
Main Author:	Wannous, Ramez
Other Authors:	Tours
Language:	fr
Published:	2014
Subjects:	PPAR DHA Cancer du sein Croissance Invasivité NaV 1.5 Breast cancer Growth Invasiveness
Online Access:	http://www.theses.fr/2014TOUR3307/document

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