Mort neuronale et maladies à prions

Mort neuronale et maladies à prions

La conversion conformationnelle de la protéine prion cellulaire PrPC neuroprotectrice en protéine prion PrPSc infectieuse et pathogène caractérise les maladies à prions. Dans le cerveau infecté par les prions, la perte de PrPC, le gain de PrPSc neurotoxique et l’inflammation concourent à la mort neu...

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Bibliographic Details
Main Author:	Ragagnin, Audrey
Other Authors:	Strasbourg
Language:	fr
Published:	2014
Subjects:	Maladies à prions Cervelet Neuroinflammation Mort neuronale Autophagie Protéine Doppel Prion diseases Cerebellum Neuronal death Autophagy Doppel 579.29 572.6 616.83
Online Access:	http://www.theses.fr/2014STRAJ094/document

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