Caractérisation moléculaire des formes métastatiques de carcinome médullaire de la thyroïde

Caractérisation moléculaire des formes métastatiques de carcinome médullaire de la thyroïde

Le carcinome médullaire de la thyroïde (CMT) est une tumeur neuroendocrine rare, se développant à partir des cellules sécrétant la calcitonine. Cette tumeur survient dans un contexte familial dans un tiers des cas. Toutes les formes germinales et près de 40% des formes sporadiques sont causées par u...

Full description

Bibliographic Details
Main Author:	Boichard, Amélie
Other Authors:	Paris 11
Language:	fr
Published:	2014
Subjects:	Carcinome médullaire de la thyroïde CMT Tumeur neuroendocrine Caractérisation moléculaire Altérations géniques Altérations chromosomiques MicroARN RET RAS Medullary thyroid carcinoma Neuroendocrine tumor Molecular characterization Gene alterations Chromosomal alterations MicroRNA
Online Access:	http://www.theses.fr/2014PA11T015/document

Similar Items

Comprehensive Assessment of Copy Number Alterations Uncovers Recurrent <i>AIFM3</i> and <i>DLK1</i> Copy Gain in Medullary Thyroid Carcinoma
by: Aline Neves Araujo, et al.
Published: (2021-01-01)

Current status of the prognostic molecular markers in medullary thyroid carcinoma
by: Malgorzata Oczko-Wojciechowska, et al.
Published: (2020-12-01)

Update on Fundamental Mechanisms of Thyroid Cancer
by: Alessandro Prete, et al.
Published: (2020-03-01)

RET mutated C-cells proliferate more rapidly than non-mutated neoplastic cells
by: Cristina Romei, et al.
Published: (2021-03-01)

MiR-4510 inhibe le développement du carcinome hépatocellulaire en ciblant RAF1 et en inhibant la voie MAPK/ERK
by: Ghousein, Amani
Published: (2018)

Genetic alterations in a primary medullary thyroid carcinoma and its lymph node metastasis in a patient with 15 years follow-up
by: González-Yebra Beatriz, et al.
Published: (2012-06-01)

Chinese siblings with hereditary medullary thyroid carcinoma caused by RET mutation: implications for RET oncogene detection
by: Qin Huang, et al.
Published: (2020-05-01)

Choice of surgery extension in medullary thyroid cancer
by: P O Rumyantsev, et al.
Published: (2011-06-01)

2012 European Thyroid Association Guidelines for Metastatic Medullary Thyroid Cancer
by: V V Voskoboynikov, et al.
Published: (2013-06-01)

Expression des microARN dans les tumeurs thyroïdiennes et leurs modèles expérimentaux in vitro
by: Floor, Sebastien
Published: (2013)

Oncocytic variant of medullary thyroid carcinoma: a rare case of sporadic multifocal and bilateral RET wild-type neoplasm with revision of the literature
by: Gian Luca Rampioni Vinciguerra, et al.
Published: (2016-12-01)

Molecular Basis of Medullary Thyroid Carcinoma: The Role of RET Polymorphisms
by: Ana Luiza Maia, et al.
Published: (2011-12-01)

Altered behavior with an organic cause: a case report
by: Dolores Mejía, et al.
Published: (2019-06-01)

Genetic alterations in anaplastic thyroid carcinoma
by: M Rashid, et al.
Published: (2019-01-01)

The Qualitative and Quantitative Structure of Oral Microbiocenosis in Rats with Periodontitis in a Setting of Hyper- and Hypothyroidism
by: Shcherba Vitaliy, et al.
Published: (2019-09-01)

Genomic characterization of high-recurrence risk papillary thyroid carcinoma in a southern Chinese population
by: Min Li, et al.
Published: (2020-05-01)

Intratumoral Heterogeneity in Differentiated Thyroid Tumors: An Intriguing Reappraisal in the Era of Personalized Medicine
by: Antonio Ieni, et al.
Published: (2021-04-01)

Selective Antitumor Activity of Datelliptium toward Medullary Thyroid Carcinoma by Downregulating RET Transcriptional Activity
by: Tariq Alqahtani, et al.
Published: (2021-06-01)

A pioneering RET genetic screening study in the State of Ceará, Brazil, evaluating patients with medullary thyroid cancer and at-risk relatives: experience with 247 individuals
by: Maria Cecília Martins-Costa, et al.

An Introduction to Managing Medullary Thyroid Cancer
by: de Groot Jan, et al.
Published: (2006-07-01)

RET mutations in a large indian family with medullary thyroid carcinoma
by: D M Mahesh, et al.
Published: (2014-01-01)

Demonstration of a potent RET transcriptional inhibitor for the treatment of medullary thyroid carcinoma based on an ellipticine derivative
by: Kumarasamy, Vishnu, et al.
Published: (2017)

A meta-analysis of prognostic roles of molecular markers in papillary thyroid carcinoma
by: Huy Gia Vuong, et al.
Published: (2017-03-01)

Génomique intégrée des tumeurs corticosurrénaliennes : implications cliniques et physiopathologiques
by: Barreau, Olivia
Published: (2013)

A Brief Review on The Molecular Basis of Medullary Thyroid Carcinoma
by: Mohammadi Masoumeh, et al.
Published: (2016-11-01)

Mechanisms and role of microRNA deregulation in cancer onset and progression
by: Edenir Inês Palmero, et al.
Published: (2011-01-01)

Modélisation des néoplasies endocriniennes multiples de type II par les cellules souches pluripotentes induites porteuses de mutations germinales du gène RET
by: Hadoux, Julien
Published: (2016)

Identification d'interacteurs moléculaires et génétiques des argonautes impliqués dans la voie des microARN chez C. Elegans
by: Rondeau, Evelyne
Published: (2008)

La séquestration de microARN dans le mélanome métastatique : du mécanisme moléculaire au candidat thérapeutique
by: Migault, Mélodie
Published: (2017)

RET/PTC translocations and clinico-pathological features in human papillary thyroid carcinoma (PTC)
by: Cristina eRomei, et al.
Published: (2012-04-01)

Genotype and phenotype landscape of MEN2 in 554 medullary thyroid cancer patients: the BrasMEN study
by: Rui M B Maciel, et al.
Published: (2019-03-01)

Twenty-Five Years Experience on RET Genetic Screening on Hereditary MTC: An Update on The Prevalence of Germline RET Mutations
by: Rossella Elisei, et al.
Published: (2019-09-01)

Germline mutation of exon 19 of RET proto-oncogene in an Iranian population with Medullary thyroid cancer
by: Hoda Golab Ghadaksaz, et al.
Published: (2015-09-01)

In vivo investigation on the chronic hepatotoxicity induced by intraperitoneal administration of 10-nm silicon dioxide nanoparticles
by: Almansour M, et al.
Published: (2018-05-01)

Simultaneous occurrence of medullary and papillary thyroid microcarcinomas: a case series and review of the literature
by: Adnan Zaina, et al.
Published: (2013-01-01)

MEDULLARY THYROID CANCER AS PART OF MEN 2B SYNDROME. CASE REPORT
by: L. N. Lyubchenko, et al.
Published: (2015-04-01)

Haplotype Frequency of G691S/S904S in the RET Proto-Onco-gene in Patients with Medullary Thyroid Carcinoma.
by: Sara Sheikholeslami, et al.
Published: (2014-02-01)

RET Copy Number Alteration in Medullary Thyroid Cancer Is a Rare Event Correlated with RET Somatic Mutations and High Allelic Frequency
by: Teresa Ramone, et al.
Published: (2021-12-01)

Medullary Thyroid Carcinoma With Exon 2 p.L56M RET Variant: Clinical Particular Features in Two Patients
by: Rosa M. Paragliola, et al.
Published: (2018-07-01)

Plasma levels of calcitonin in medullary thyroid carcinoma patients with and without the RET proto-oncogene mutations in exons 10 and 11
by: Samira Ehyayi, et al.
Published: (2017-09-01)