Describing novel pathways involved in the onset of telomere-dependent replicative senescence in Saccharomyces cerevisiae
Les chromosomes linéaires se terminent par des régions particulières, les télomères, qui assurent l'intégrité et la stabilité du génome. Chez les eucaryotes, les télomères déterminent également le potentiel de prolifération de cellules en déclenchant la sénescence réplicative. Ce signal se prod...
Main Author: | Serhal, Kamar Al Zaman |
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Other Authors: | Paris 6 |
Language: | en |
Published: |
2014
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Subjects: | |
Online Access: | http://www.theses.fr/2014PA066625/document |
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