The role of the histone variant cenp-a and its chaperone hjurp in mouse centromere propagation and tumorigenesis

The role of the histone variant cenp-a and its chaperone hjurp in mouse centromere propagation and tumorigenesis

Les centromères contribuent à garantir la distribution égale de l'ADN en mitose. Leur identité n'est pas codifiée par la séquence d'ADN, mais de manière épigénétique par le variant de l'histone H3 CENP-A. Dans des lignées cellulaires humaines transformées, CENP-A est incorporé au...

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Bibliographic Details
Main Author:	Filipescu, Dan
Other Authors:	Paris 6
Language:	en
Published:	2014
Subjects:	Centromère Cenp-a Hjurp Tumorigenèse Développement H2a.z Centromere Heterochromatin 571.6
Online Access:	http://www.theses.fr/2014PA066170

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