Neuronal polarization shapes the targeting and signaling of G-protein coupled receptors (GPCRs) : type-1 cannabinoid receptors and 5-HT1B serotonin receptors show highly contrasted trafficking and signaling patterns in axons and dendrites
L’architecture polarisée des neurones est mise en place est maintenue grâce à un adressage hautement contrôlé de protéines vers l’axone ou vers le compartiment somatodendritique. Parmi ces protéines, les récepteurs aux protéines G (RCPG) neuronaux sont des cibles pharmacologiques clés. Cependant, le...
Main Author: | Ladarré, Delphine |
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Other Authors: | Paris 5 |
Language: | en |
Published: |
2014
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Subjects: | |
Online Access: | http://www.theses.fr/2014PA05T070/document |
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