Structural and functional study of efflux pumps involved in drug resistance
L’efficacité des chimiothérapies est limitée par la surexpression de pompes d’efflux adressées à la membrane plasmique des cellules cibles. En effet, celles-ci réduisent le taux intracellulaire des médicaments anticancéreux, antiviraux, antifongiques et antibactériens. La P-gp/ABCB1 est la plus impl...
Main Author: | Martinez Jaramillo, Lorena Marcela |
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Other Authors: | Lyon 1 |
Language: | en |
Published: |
2014
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Subjects: | |
Online Access: | http://www.theses.fr/2014LYO10017/document |
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