Déterminants moléculaires de la néphrotoxicité induite par le tacrolimus après transplantation rénale

Déterminants moléculaires de la néphrotoxicité induite par le tacrolimus après transplantation rénale

Bien que le Tacrolimus soit un immunosuppresseur largement prescrit en transplantation rénale, ses effets néphrotoxiques limitent son utilisation. En effet, le Tacrolimus contribue au développement de lésions de fibrose interstitielle rénale et d’atrophie tubulaire à plus ou moins brève échéance. Pa...

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Bibliographic Details
Main Author:	Van Der Hauwaert, Cynthia
Other Authors:	Lille 2
Language:	fr
Published:	2014
Subjects:	Néphrotoxicité Tacrolimus Fibrose Néphrotoxicologie Transplantation rénale Renal Transplantation Fibroses Genetic Polymorphism
Online Access:	http://www.theses.fr/2014LIL2S033/document

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