Inhibition de l'angiogenèse tumorale : criblage d'une chimiothèque et caractérisation d'un nouveau composé agissant sur la voie de signalisation Ras-ERK

Inhibition de l'angiogenèse tumorale : criblage d'une chimiothèque et caractérisation d'un nouveau composé agissant sur la voie de signalisation Ras-ERK

Au cours des dernières années, des thérapies anti-cancéreuses ciblant l'angiogenèse tumorale ont été développées et ont démontré un bénéfice en terme de survie globale pour les patients atteints de certains cancers métastatiques. Cependant, dans de nombreux cas, les tumeurs acquièrent des résis...

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Bibliographic Details
Main Author:	Castan, Agnès
Other Authors:	Grenoble
Language:	fr
Published:	2014
Subjects:	Angiogenèse tumorale Signalisation du VEGF Signalisation Ras-Raf-ERK Chimiothèque Composées anti-angiogènes Tumor angiogenesis VEGF signaling Ras-Raf-ERK pathway Chemical library Anti-angiogenic agents 610
Online Access:	http://www.theses.fr/2014GRENV017/document

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