Les variants d'épissage du VEGF-A : leur rôle dans la progression et la réponse aux thérapies anti-angiogéniques des carcinomes pulmonaires

Les variants d'épissage du VEGF-A : leur rôle dans la progression et la réponse aux thérapies anti-angiogéniques des carcinomes pulmonaires

Le VEGF-A est l'un des facteurs de croissance les plus importants au cours de la néo-angiogénèse tumorale. Ce rôle en a fait une cible de choix pour le développement de thérapies. Ainsi, différents médicaments le ciblant (Bevacizumab, AvastinR) ou ciblant ses voies de signalisation (inhibiteurs...

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Bibliographic Details
Main Author:	Boudria, Asma
Other Authors:	Grenoble
Language:	fr
Published:	2014
Subjects:	VEGF-A Thérapies anti-angiogéniques Epissage alternatif Ratio VEGFxxxb/panVEGF Cancer du poumon Antiangiogenic therapies Alternative splicing VEGFxxxb/panVEGF ratio Lung cancer
Online Access:	http://www.theses.fr/2014GRENV010/document

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