Potentialisation de la virothérapie anti-tumorale basée sur des adénovirus oncolytiques dans le traitement des cancers côliques et rénaux

Potentialisation de la virothérapie anti-tumorale basée sur des adénovirus oncolytiques dans le traitement des cancers côliques et rénaux

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Nous avons mis en place au cours de ce travail de thèse différentes stratégies permettant d’améliorer l’efficacité thérapeutique des adénovirus (Ad) oncolytiques contre différents types de tumeurs. Une première stratégie a été de combiner un inhibiteur d’histone-désacétylase, l’acide valproique (VPA...

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Bibliographic Details
Main Author:	Bressy, Christian
Other Authors:	Paris 11
Language:	fr
Published:	2013
Subjects:	Adénovirus oncolytiques Cancer HDACi Acide valproique Capside modifiée Oncolytic adenovirus Valproic acid Modified-capsid
Online Access:	http://www.theses.fr/2013PA11T020/document

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