Modulation des voies de présentation antigénique et induction de lymphocytes T régulateurs pour la thérapie génique

Modulation des voies de présentation antigénique et induction de lymphocytes T régulateurs pour la thérapie génique

L’expression d’un transgène grâce au vecteur AAV offre une perspective thérapeutique très prometteuse dans le traitement de maladies monogéniques. Malheureusement, il apparait souvent que des réponses immunes contre le vecteur et le transgène conduisent à un rejet des cellules transduites ainsi qu’à...

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Bibliographic Details
Main Author:	Carpentier, Maxime
Other Authors:	Paris 5
Language:	fr
Published:	2013
Subjects:	Virus adéno-associés Thérapie génique Réponse immunitaire MiR142.3p Treg Foxp3 Sénescence Adeno-associated virus Gene therapy Immune response Senescence 616.079
Online Access:	http://www.theses.fr/2013PA05T081

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