Les thérapies anti-angiogéniques : entre espoir et réalité. Vers l'identification de marqueurs prédictifs et de nouvelles cibles thérapeutiques dans le traitement du cancer du rein

Les thérapies anti-angiogéniques : entre espoir et réalité. Vers l'identification de marqueurs prédictifs et de nouvelles cibles thérapeutiques dans le traitement du cancer du rein

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L’ensemble de ce travail vise à étudier les mécanismes de résistance aux thérapies anti-angiogéniques dans le traitement du cancer du rein à cellules claires (ccRCC). Nous avons mis en évidence que le bévacizumab (BVZ), un anticorps monoclonal humanisé anti-VEGF utilisé en clinique, accélère la croi...

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Bibliographic Details
Main Author:	Guyot, Mélanie
Other Authors:	Nice
Language:	fr
Published:	2013
Subjects:	Angiogenèse Traitements anti-angiogéniques Résistances CcRCC Marqueurs prédictifs et pronostiques Angiogenesis Anti-angiogenic therapy Resistance Predictive and prognostic markers
Online Access:	http://www.theses.fr/2013NICE4056/document

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