Etude des mécanismes moléculaires de résistance différentielle du mélanome malin aux vincalcaloïdes

Etude des mécanismes moléculaires de résistance différentielle du mélanome malin aux vincalcaloïdes

Le mélanome malin (MM) est un cancer très réfractaire aux thérapies anticancéreuses, dont les vincalcaloïdes (VAs). Afin d'étudier le rôle de la GSTM1 (glutathion S-transférase 1) et la MRP1 (multidrug resistance protein 1) dans la résistance acquise du MM aux VAs, nous avons établi 4 modèles c...

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Bibliographic Details
Main Author:	Attaoua, Chaker
Other Authors:	Montpellier 1
Language:	fr
Published:	2013
Subjects:	Mélanome malin Chimiorésistance Vincalcaloïdes Glutathion S-transférase Mu1 Multidrug resistance proteins 1 Transcriptome Malignant melanoma Chemoresistance Vinca alkaloids Glutathione S-transferase Mu1 616
Online Access:	http://www.theses.fr/2013MON13505

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