Optimisation de nanoparticules multifonctionnelles pour une amélioration de l'efficacité photodynamique, de la sélectivité tumorale et de la détection par IRM

Optimisation de nanoparticules multifonctionnelles pour une amélioration de l'efficacité photodynamique, de la sélectivité tumorale et de la détection par IRM

La thérapie photodynamique (PDT pour Photodynamic Therapy) met en jeu des molécules nommées photosensibilisateurs (PS), de l'oxygène et de la lumière. Les PS, non cytotoxiques à l'obscurité, produisent des espèces réactives de l'oxygène (ROS) lorsqu'ils sont excités avec une long...

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Bibliographic Details
Main Author:	Seve, Aymeric
Other Authors:	Université de Lorraine
Language:	fr
Published:	2013
Subjects:	ATWLPR DOTA DTPA Gd2O3 Glioblastome IRM MDA-MB-231 Nanoparticules multifonctionnelles Néovaisseaux Neuropiline 1 NRP-1 PDT Oxygène singulet Photosensibilisateurs Polysiloxane U87 Glioblastoma Multifunctional nanoparticles Neovessels Neuropilin 1 Photosensitizer Polysiloxan Singlet oxygen 616.994 0631
Online Access:	http://www.theses.fr/2013LORR0174/document

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