Improvement of dissolution rate of a new antiretroviral drug using an anti-solvent crystallization technology

Improvement of dissolution rate of a new antiretroviral drug using an anti-solvent crystallization technology

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Cette étude concerne une nouvelle molécule antirétrovirale nommée CRS 74. Cette molécule présente une biodisponibilité limitée à cause de sa faible solubilité en phase aqueuse, sa mauvaise mouillabilité et sa faible vitesse de dissolution. Afin d'améliorer sa biodisponibilité, la molécule CRS...

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Bibliographic Details
Main Author:	Paiva Lacerda, Suênia de
Other Authors:	Toulouse, INPT
Language:	en
Published:	2013
Subjects:	Molécule active antirétrovirale Solubilité Vitesse de dissolution Cristallisation par effet anti-solvant Additifs Biodisponibilité Antiretroviral drug Solubility Bioavailability Dissolution rate Liquid Anti Solvent crystallization Additive
Online Access:	http://www.theses.fr/2013INPT0006/document

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