Dysfonctions mitochondriales et homéostasie bioénergétique des motoneurones dans un modèle de sclérose latérale amyotrophique

Dysfonctions mitochondriales et homéostasie bioénergétique des motoneurones dans un modèle de sclérose latérale amyotrophique

La sclérose latérale amyotrophique (SLA) est une maladie neurodégénérative fatale de l'âge adulte, caractérisée par une perte de motoneurones, conduisant à une atrophie et une faiblesse musculaires. Des mutations de la superoxyde dismutase-1 (SOD1) provoquent une forme génétique de SLA. Comme c...

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Bibliographic Details
Main Author:	Allard, Ludivine
Other Authors:	Bordeaux 2
Language:	fr
Published:	2013
Subjects:	Mitochondrie Motoneurone Bioénergétique Découplage SOD1 SLA Mitochondria Motoneurons Bioenergetic Uncoupling ALS
Online Access:	http://www.theses.fr/2013BOR22088/document

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