Amélioration rationalisée de l'enzyme hyperthermostable SsoPOX. : Perpespectives de développement d'un bio-décontaminant d'organophosphorés et d'un agent anti-virulence bactérienne.

Amélioration rationalisée de l'enzyme hyperthermostable SsoPOX. : Perpespectives de développement d'un bio-décontaminant d'organophosphorés et d'un agent anti-virulence bactérienne.

Issue de l'Archaea extrêmophile Sulfolobus solfataricus, SsoPox est une enzyme à fort potentiel biotechnologique du fait de son extrême stabilité. Nous avons caractérisé son activité lactonase naturelle ainsi que son activité de promiscuité phosphotriestérase. Elle est capable d'hydrolyser...

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Bibliographic Details
Main Author:	Hiblot, Julien
Other Authors:	Aix-Marseille
Language:	fr
Published:	2013
Subjects:	Lactonase Quorum sensing Phosphotriestérase Organophosphoré Hyperthermostable Evolution rationalisé Promiscuité enzymatique Flexibilité conformatonnelle Organophosphorus Rational evolution Enzymatic promiscuity Conformatonnal flexibility 572
Online Access:	http://www.theses.fr/2013AIXM4024

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