Implication fonctionnelle du récepteur P2X7 dans les mécanismes neuroinflammatoires associés à la dépression : étude préclinique

Implication fonctionnelle du récepteur P2X7 dans les mécanismes neuroinflammatoires associés à la dépression : étude préclinique

Le projet de cette thèse s'est attaché à caractériser le rôle de l'IL-1 beta et les récepteurs P2X7 dans la dépression. Les résultats suggèrent que chez les souris stressés et les perturbation comportementaux, l'activation microgliales et endocriniennes sont reversées par l'antag...

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Bibliographic Details
Main Author:	Farooq, Rai Khalid
Other Authors:	Tours
Language:	en
Published:	2012
Subjects:	Neuroinflammation Axe HPA Major depression UCMS P2X7 receptor Neurogenesis HPA-axis Antidepressant resistance IL-1β Microglia
Online Access:	http://www.theses.fr/2012TOUR4022/document

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