Blood-Brain Barrier during cerebral maturation : impact of neuro-inflammation on the regulation of drug-efflux/influx transporters

Blood-Brain Barrier during cerebral maturation : impact of neuro-inflammation on the regulation of drug-efflux/influx transporters

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L’échec thérapeutique des maladies cérébrales est lié, entre autres, à la présence de barrières entre le sang et le Système Nerveux Central (SNC), en particulier la Barrière Hémato-Encéphalique (BHE). La BHE est une structure neuro-vasculaire localisée au niveau des MicroVaisseaux Cérébraux (MVC) li...

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Bibliographic Details
Main Author:	Harati, Rania
Other Authors:	Paris 11
Language:	en
Published:	2012
Subjects:	BHE Barrière hémato-encéphalique Transporteurs ABC Transporteurs SLC P-gp Bcrp Oat3 Oatp1a4 Maturation cérébrale Ontogenèse Inflammation Voie de signalisation Wnt/β-caténine Endothéline-1 Blood-brain barrier ABC transporters Ontogenesis Brain maturation Endothelin-1 Wnt/β-catenin signaling
Online Access:	http://www.theses.fr/2012PA114856/document

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