Propriétés et mécanisme d'action des analogues de choline, une nouvelle classe d'antipaludiques. Etude de l'albitiazolium, candidat clinique.

Propriétés et mécanisme d'action des analogues de choline, une nouvelle classe d'antipaludiques. Etude de l'albitiazolium, candidat clinique.

Les analogues de choline constituent une nouvelle classe d'antipaludiques qui inhibent la biosynthèse de la phosphatidylcholine (PC) de Plasmodium, parasite responsable du paludisme. Les études conduites ont mis en relief des particularités uniques de ces composés. Nous avons élucidé le mécanis...

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Bibliographic Details
Main Author:	Wein, Sharon
Other Authors:	Montpellier 2
Language:	fr
Published:	2012
Subjects:	Plasmodium Paludisme Phospholipides Chimiothérapie Analogue de choline Mécanisme d'action Malaria Phospholipid Chemotherapy Choline analogue Mechanism of action
Online Access:	http://www.theses.fr/2012MON20078

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