Exploration fonctionnelle de protéines mitochondriales et étude du protéasome 'mitochondrial' HslVU, cible thérapeutique potentielle, chez les Trypanosomatidés.
Leishmania et Trypanosoma brucei sont des protozoaires parasites responsables de graves parasitoses de distribution mondiale. Aucun vaccin n'est disponible contre ces maladies dont le traitement reste basé sur un nombre limité de médicaments coûteux, souvent toxiques et peu efficaces, problème...
Main Author: | Mbang-Benet, Diane-Ethna |
---|---|
Other Authors: | Montpellier 1 |
Language: | fr |
Published: |
2012
|
Subjects: | |
Online Access: | http://www.theses.fr/2012MON1T010/document |
Similar Items
-
Etude du protéasome "ancestral" HslVU de Leishmania major
by: Kebe, Ndeye Mathy
Published: (2012) -
The HslV Protease from <i>Leishmania major</i> and Its Activation by C-terminal HslU Peptides
by: Ndeye Mathy Kebe, et al.
Published: (2019-02-01) -
Trypanosomatid comparative genomics: contributions to the study of parasite biology and different parasitic diseases
by: Santuza M. Teixeira, et al.
Published: (2012-01-01) -
Codon usage bias controls mRNA and protein abundance in trypanosomatids
by: Laura Jeacock, et al.
Published: (2018-03-01) -
Ubiquitination and the Proteasome as Drug Targets in Trypanosomatid Diseases
by: Marie-José Bijlmakers
Published: (2021-01-01)