Design of an internet tool to assess variants of uncertain clinical significance in high-risk breast cancer genes BRCA1 and BRCA2

Design of an internet tool to assess variants of uncertain clinical significance in high-risk breast cancer genes BRCA1 and BRCA2

Des mutations germinales dans les gènes majeurs du cancer du sein BRCA1 et BRCA2 sont responsables de la maladie chez les patientes cumulant histoire familiale et apparition du cancer à un jeune âge. Environ 15% des femmes testées pour les mutations de BRCA1 et BRCA2 sont porteuses d’une mutation cl...

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Bibliographic Details
Main Author:	Vallée, Maxime
Other Authors:	Lyon 1
Language:	en
Published:	2012
Subjects:	Cancer du sein Prédisposition génétique BRCA1 BRCA2 Variant UV Épissage Évaluation Breast cancer Genetic susceptibility Splicing Evaluation 570.285
Online Access:	http://www.theses.fr/2012LYO10193

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