Connaissance des facteurs déterminants dans la conduite d'un procédé pour la production de toxine par Corynebacterium diphteriae utilisée dans la formulation de vaccins

Connaissance des facteurs déterminants dans la conduite d'un procédé pour la production de toxine par Corynebacterium diphteriae utilisée dans la formulation de vaccins

Avec pour problématique une importante variabilité des lots de production vaccinale contre la diphtérie, une analyse intégrative du métabolisme central, du fer et du transcriptome de Corynebacterium diphtheriae, cultivé en conditions les plus proches de la culture industrielle, ont permis d’élargir...

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Bibliographic Details
Main Author:	Gauriat, Marie-Anne
Other Authors:	Toulouse, INSA
Language:	fr
Published:	2012
Subjects:	Corynebacterium diphtheriae Vaccine Toxine DtxR Fer Maltose Ferritine Virulence Métabolisme Transcriptome Toxin Iron Ferritin Metabolism 660.62 615.372
Online Access:	http://www.theses.fr/2012ISAT0041/document

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