Impact fonctionnel de l' oncogène TLX3 sur la thymopoïse dans les leucémies aiguës lymphoblastiques T .

Impact fonctionnel de l' oncogène TLX3 sur la thymopoïse dans les leucémies aiguës lymphoblastiques T .

Les membres de la famille Homeobox jouent un rôle critique dans le développement hématopoïétique normal. L'expression ectopique des gènes Homeobox provoque des désordres dans l'hématopoïèse et le développement de leucémies. L'oncogène TLX3 s'exprime de manière ectopique exclusive...

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Bibliographic Details
Main Author:	Kazheunikava, Larysa
Other Authors:	Aix-Marseille
Language:	en
Published:	2012
Subjects:	Lal-t TLX3 proto-oncogène Développement lymphocytaire T Facteur de transcription Ets1 Runx1 Enhancers Éléments cis-régulateurs T-all TLX3 proto-oncogene T-cell development Transcription factor Cis-regulatory elements
Online Access:	http://www.theses.fr/2012AIXM4046

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