Impact des isoformes du récepteur de la progestérone sur la progression métastatique du cancer du sein : étude in vitro de la motilité de la lignée MDA-MB-231

Impact des isoformes du récepteur de la progestérone sur la progression métastatique du cancer du sein : étude in vitro de la motilité de la lignée MDA-MB-231

Le récepteur de la progestérone (PR) est un acteur majeur du développement de la glande mammaire. Dans les cellules épithéliales normales, PR est exprimé sous deux isoformes PRA (94 kDa) et PRB (116 kDa) de façon équimolaire. Il est établi que celles-ci ont un impact important sur le développement d...

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Bibliographic Details
Main Author:	Bellance, Catherine
Other Authors:	Paris 11
Language:	fr
Published:	2011
Subjects:	Récepteur de la progestérone Cancer du sein Métastases FAK Système uPA MAPK MDA-MB 231 Progesterone receptor Breast cancer Metastasis UPA system
Online Access:	http://www.theses.fr/2011PA11T090

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