Modules réactionnels : un nouveau concept pour étudier l'évolution des voies métaboliques

Modules réactionnels : un nouveau concept pour étudier l'évolution des voies métaboliques

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J'ai mis au point une méthodologie pour annoter les superfamilles d'enzymes, en décrire l'histoire et les replacer dans l'évolution de leurs voies métaboliques. J'en ai étudié trois : (1) les amidohydrolases cycliques, dont les DHOases (dihydroorotases, biosynthèse des pyrim...

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Bibliographic Details
Main Author:	Barba, Matthieu
Other Authors:	Paris 11
Language:	fr
Published:	2011
Subjects:	Alignement multiple Arbre phylogénétique Superfamille Amidohydrolase Dihydroorotase Carbamoyltransférase Voie métabolique Réaction chimique Ambigüité de substrat Module réactionnel Multiple sequence alignment Phylogenetic tree Carbamoyltransferase Metabolic pathway Chemical reaction Substrate ambiguity Reaction module
Online Access:	http://www.theses.fr/2011PA112319/document

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