Caractérisation de nouveaux substrats moléculaires des agonistes hallucinogènes du récepteur 5-HT2A par une approche phosphoprotéomique quantitative.

Caractérisation de nouveaux substrats moléculaires des agonistes hallucinogènes du récepteur 5-HT2A par une approche phosphoprotéomique quantitative.

Le récepteur de la sérotonine (5-hydroxytryptamine, 5-HT) 2A a été identifié comme la cible principale des hallucinogènes psychédéliques comme le diéthylamide de l'acide lysergique (LSD). Ces agonistes sont connus pour reproduire quelques uns des principaux symptômes de la schizophrénie. Un par...

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Bibliographic Details
Main Author:	Karaki, Samah
Other Authors:	Montpellier 2
Language:	fr
Published:	2011
Subjects:	Récepteurs 5-HT2A Approche phosphoprotéomique. Effets psychoactifs Composés hallucinogènes Agonistes biaisés Rsk2 5-HT2A receptors Phosphoproteomics approach Psychoactive effects Hallucinogenic compounds Biased agonists
Online Access:	http://www.theses.fr/2011MON20153

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