Systèmes protéolytiques ciblant la protéine multi-adaptatrice GAB1 dans la régulation de la signalisation HGF/SF-MET

Systèmes protéolytiques ciblant la protéine multi-adaptatrice GAB1 dans la régulation de la signalisation HGF/SF-MET

La protéine multi-adaptatrice GAB1 (GRB2-associated binder-1) est essentielle pour transmettre la signalisation et les réponses biologiques du récepteur tyrosine kinase MET activé par son ligand, l’HGF/SF (Hepatocyte Growth Factor/Scatter Factor), et joue un rôle positif dans de nombreuses autres vo...

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Bibliographic Details
Main Author:	Le Goff, Arnaud
Other Authors:	Lille 2
Language:	fr
Published:	2011
Subjects:	GAB1 Dégradation protéasomale
Online Access:	http://www.theses.fr/2011LIL2S026

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