Nouvelles fonctions de p21Cip1 dans la dynamique cytosquelettique des cellules épithéliales mammaires humaines

Nouvelles fonctions de p21Cip1 dans la dynamique cytosquelettique des cellules épithéliales mammaires humaines

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Le gène CDKN1A a été initialement décrit comme une cible transcriptionnelle de la protéineoncosuppressive p53. Son produit, p21Cip1 (p21), supprime l’activité des kinases dépendantes descyclines et de la protéine PCNA, ce qui en fait un puissant inhibiteur du cycle et de la proliférationcellulaires....

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Bibliographic Details
Main Author:	Bouchet, Benjamin
Other Authors:	Lyon 1
Language:	fr
Published:	2010
Subjects:	P21 Adhésion Cytosquelette Actine Microtubules Cancer du sein Adhesion Cytoskeleton Actin Breast cancer 571
Online Access:	http://www.theses.fr/2010LYO10056/document

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