Synthesis, Characterization, and Applications of a Melamine Based Dendrimer with Twelve Cysteine Groups on the Periphery

A potential drug delivery vehicle based on a melamine dendrimer with twelve free thiols on the periphery for constructing bio-labile disulfides has been synthesized. Under ideal conditions for the native chemical ligation reaction, attempts for attaching the cell penetrating peptide TAT, via native...

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Bibliographic Details
Main Author: Vittur, Brandon M.
Other Authors: Simanek, Eric E.
Format: Others
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7549