New mechanism-based anticancer drugs that act as orphan nuclear receptor agonists
1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes containing ptrifluoromethyl (DIM-C-pPhCF3), p-t-butyl (DIM-C-pPhtBu), and phenyl (DIM-CpPhC6H5) substituents have been identified as a new class of peroxisome proliferatoractivated receptor ó (PPARó) agonists that exhibit antitumorigenic...
Main Author: | Chintharlapalli, Sudhakar Reddy |
---|---|
Other Authors: | Safe, Stephen |
Format: | Others |
Language: | en_US |
Published: |
Texas A&M University
2007
|
Subjects: | |
Online Access: | http://hdl.handle.net/1969.1/5978 |
Similar Items
-
The orphan nuclear receptor Nur77 plays a vital role in BPA-induced PC12 cell apoptosis
by: Yingchun Zhang, et al.
Published: (2021-04-01) -
Cantharidin Induces Apoptosis and Promotes Differentiation of AML Cells Through Nuclear Receptor Nur77-Mediated Signaling Pathway
by: Zanyang Yu, et al.
Published: (2020-08-01) -
Relevance of the NR4A sub-family of nuclear orphan receptors in trophoblastic BeWo cell differentiation
by: Sudha Saryu Malhotra, et al.
Published: (2017-08-01) -
Memantine inhibits 6-OHDA-induced apoptosis PC12 cells via the Nurr77 and caspase pathway
by: Wei Wu, et al.
Published: (2019-01-01) -
Role of the Orphan Nuclear Receptor NR4A Family in T-Cell Biology
by: Livia Odagiu, et al.
Published: (2021-02-01)