New mechanism-based anticancer drugs that act as orphan nuclear receptor agonists

New mechanism-based anticancer drugs that act as orphan nuclear receptor agonists

1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes containing ptrifluoromethyl (DIM-C-pPhCF3), p-t-butyl (DIM-C-pPhtBu), and phenyl (DIM-CpPhC6H5) substituents have been identified as a new class of peroxisome proliferatoractivated receptor γ (PPARγ) agonists that exhibit antitumorigenic...

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Bibliographic Details
Main Author: Chintharlapalli, Sudhakar Reddy
Other Authors: Safe, Stephen
Format: Others
Language:en_US
Published: Texas A&M University 2007
Subjects:
C-DIMs
PPAR gamma
Nur77
Apoptosis
Anticancer Drugs
Caveolin-1
Online Access:http://hdl.handle.net/1969.1/5978

Internet

http://hdl.handle.net/1969.1/5978

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