A Role for PFKFB3/IPFK2 in Overnutrition-Associated Adipose Tissue and Intestine Inflammatory Responses and Insulin Resistance

Overnutrition causes many metabolic diseases including type 2 diabetes. PFKFB3/iPFK2 is a master regulator of adipocyte and intestinal nutrient metabolism. Using PFKFB3/iPFK2+/– mice and adipocyte-specific PFKFB3 over-expression mice, the present study investigated the role of PFKFB3/iPFK2 in regula...

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Bibliographic Details
Main Author: Guo, Xin
Other Authors: Wu, Chaodong
Format: Others
Language:en
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1969.1/149413