Functional Separation of Multimodular Type I PKS Polypeptides by Utilizing Matched Docking Domains From a Heterologous PKS System

Bacterial type I modular polyketide synthases (PKS) are large multifunctional enzyme systems responsible for the biosynthesis of complex polyketide natural products such as erythromycin, pikromycin, and borrelidin. Type I systems are comprised of a loading module which generally selects an appropria...

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Bibliographic Details
Main Author: Yan, John Kam
Format: Others
Published: PDXScholar 2010
Subjects:
Online Access:https://pdxscholar.library.pdx.edu/open_access_etds/135
https://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=1134&context=open_access_etds

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