Functional Separation of Multimodular Type I PKS Polypeptides by Utilizing Matched Docking Domains From a Heterologous PKS System
Bacterial type I modular polyketide synthases (PKS) are large multifunctional enzyme systems responsible for the biosynthesis of complex polyketide natural products such as erythromycin, pikromycin, and borrelidin. Type I systems are comprised of a loading module which generally selects an appropria...
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PDXScholar
2010
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Online Access: | https://pdxscholar.library.pdx.edu/open_access_etds/135 https://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=1134&context=open_access_etds |