Examination of posterior predictive check and bootstrap as population model validation tools
Drug development is time consuming, expensive with high failure rates. It takes 10-15 years for a drug to go from discovery to approval, while the mean cost of developing a drug is $1.5 billions dollars. Pharmacometric models (PM) play a pivotal role in knowledge driven drug development and these mo...
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Scholarly Commons
2008
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| Online Access: | https://scholarlycommons.pacific.edu/uop_etds/2381 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=3380&context=uop_etds |