Design, synthesis, and biological evaluation of inhibitors for N⁸-acetyspermidine deacetglase and spermidine N⁸-acetytransferase
Previous studies active-site-directed metal coordinating reagents and substrate analogues of (N8-AcSpd) have indicated that the catalytic mechanism of N8-AcSpd deacetylase involved a transition state metal. Several ω-amino substituted carboxylic acids were tested and results confirmed the probabilit...
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| Format: | Others |
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Scholarly Commons
1989
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| Online Access: | https://scholarlycommons.pacific.edu/uop_etds/2179 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=3178&context=uop_etds |