Induction and characterization of de novo methylation by benzo[A]pyrene in the cancer cell lines MCF-7 and MDA-MB-231

The experiments presented were designed to test the hypothesis that the well-known carcinogen, benzo[a]pyrene has epigenetic effects, specifically the ability to alter cytosine methylation patterns. MCF-7 and MDA-MB-231 human breast cancer cells were treated for a period of sixty days with 100 nM be...

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Bibliographic Details
Main Author: Kozina, Vladimir Joseph
Format: Others
Published: Scholarly Commons 2005
Subjects:
Online Access:https://scholarlycommons.pacific.edu/uop_etds/609
https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1608&context=uop_etds