3-amino-2,5-dihydroxy-5-sulfo-benzoic acid
It seems possible that efforts to discover essential chemical differences which might exist between normal and malignant cells will eventually reveal the secret of cancer and thereby lead to new approaches to safer and more selective chemotherapy. One objective of this study is to find that part of...
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Scholarly Commons
1960
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| Online Access: | https://scholarlycommons.pacific.edu/uop_etds/367 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1366&context=uop_etds |
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ndltd-pacific.edu-oai-scholarlycommons.pacific.edu-uop_etds-13662021-10-05T05:13:08Z 3-amino-2,5-dihydroxy-5-sulfo-benzoic acid Tomomatsu, Hideo It seems possible that efforts to discover essential chemical differences which might exist between normal and malignant cells will eventually reveal the secret of cancer and thereby lead to new approaches to safer and more selective chemotherapy. One objective of this study is to find that part of this molecule that causes it to concentrate in the tumor and thence make a smaller size compound which has similar concentration characteristics to tumor as tetracycline. For this purpose, an attempt was made in this study to synthesize the right side ring of Chlorotetracycline, the structure of which is shown below. [see PDF] 1960-01-01T08:00:00Z text application/pdf https://scholarlycommons.pacific.edu/uop_etds/367 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1366&context=uop_etds University of the Pacific Theses and Dissertations Scholarly Commons University of the Pacific Dissertations Chemistry Physical Sciences and Mathematics |
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Others
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University of the Pacific Dissertations Chemistry Physical Sciences and Mathematics |
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University of the Pacific Dissertations Chemistry Physical Sciences and Mathematics Tomomatsu, Hideo 3-amino-2,5-dihydroxy-5-sulfo-benzoic acid |
| description |
It seems possible that efforts to discover essential chemical differences which might exist between normal and malignant cells will eventually reveal the secret of cancer and thereby lead to new approaches to safer and more selective chemotherapy.
One objective of this study is to find that part of this molecule that causes it to concentrate in the tumor and thence make a smaller size compound which has similar concentration characteristics to tumor as tetracycline. For this purpose, an attempt was made in this study to synthesize the right side ring of Chlorotetracycline, the structure of which is shown below. [see PDF] |
| author |
Tomomatsu, Hideo |
| author_facet |
Tomomatsu, Hideo |
| author_sort |
Tomomatsu, Hideo |
| title |
3-amino-2,5-dihydroxy-5-sulfo-benzoic acid |
| title_short |
3-amino-2,5-dihydroxy-5-sulfo-benzoic acid |
| title_full |
3-amino-2,5-dihydroxy-5-sulfo-benzoic acid |
| title_fullStr |
3-amino-2,5-dihydroxy-5-sulfo-benzoic acid |
| title_full_unstemmed |
3-amino-2,5-dihydroxy-5-sulfo-benzoic acid |
| title_sort |
3-amino-2,5-dihydroxy-5-sulfo-benzoic acid |
| publisher |
Scholarly Commons |
| publishDate |
1960 |
| url |
https://scholarlycommons.pacific.edu/uop_etds/367 https://scholarlycommons.pacific.edu/cgi/viewcontent.cgi?article=1366&context=uop_etds |
| work_keys_str_mv |
AT tomomatsuhideo 3amino25dihydroxy5sulfobenzoicacid |
| _version_ |
1719487440177070080 |