Incorporation of non-canoncical amino acids into recombinant human proteins heterologously expressed in E. coli by bioprocess parturbations
The purity of heterologous recombinant proteins is of utmost importance to the pharmaceutical sector since most are consumed as therapeutic agents by humans. Variability caused by co- and posttranslational modifications is a major concern in pharmaceutical production. In order to develop strategies...
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| Format: | Dissertation |
| Language: | English |
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University of Oulu
2014
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| Online Access: | http://urn.fi/URN:NBN:fi:oulu-201406121759 http://nbn-resolving.de/urn:nbn:fi:oulu-201406121759 |