In vitro methods in the study of reactive drug metabolites with liquid chromatography / mass spectrometry
Abstract Reactive metabolites are believed to be responsible for rare but serious idiosyncratic adverse drug reactions (IADRs) that have led to the withdrawal of numerous drugs from the market. This has resulted in major harm to patients, economic losses for the pharmaceutical companies and represe...
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Format: | Doctoral Thesis |
Language: | English |
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Oulun yliopisto
2016
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Online Access: | http://urn.fi/urn:isbn:9789526212197 http://nbn-resolving.de/urn:isbn:9789526212197 |