In vitro methods in the study of reactive drug metabolites with liquid chromatography / mass spectrometry

Abstract Reactive metabolites are believed to be responsible for rare but serious idiosyncratic adverse drug reactions (IADRs) that have led to the withdrawal of numerous drugs from the market. This has resulted in major harm to patients, economic losses for the pharmaceutical companies and represe...

Full description

Bibliographic Details
Main Author: Lassila, T. (Toni)
Other Authors: Mattila, S. (Sampo)
Format: Doctoral Thesis
Language:English
Published: Oulun yliopisto 2016
Subjects:
Online Access:http://urn.fi/urn:isbn:9789526212197
http://nbn-resolving.de/urn:isbn:9789526212197