Characterization of signaling mechanisms regulating cardiac contractility
Abstract The heart adapts to hemodynamic overload with cardiac hypertrophy. Initially the increase in heart mass normalizes wall stress and permits normal cardiac function. In the long term pathological growth is associated with increased heart size, loss of functional myocytes and fibrotic replace...
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| Format: | Doctoral Thesis |
| Language: | English |
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Oulun yliopisto
2011
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| Online Access: | http://urn.fi/urn:isbn:9789514294433 http://nbn-resolving.de/urn:isbn:9789514294433 |