Genetic causes of mitochondrial complex I deficiency in children
Abstract The mitochondrial oxidative phosphorylation system is composed of five multisubunit enzyme complexes. Complex I is the first and largest of these, containing 46 subunits, seven encoded by mitochondrial DNA (mtDNA) and the rest by nuclear DNA. Isolated complex I deficiency is a major cause...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2006
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| Online Access: | http://urn.fi/urn:isbn:9514282884 http://nbn-resolving.de/urn:isbn:9514282884 |