Matrix metalloproteinases -2 and -9 and tissue inhibitors of metalloproteinases -1 and -2 in gynaecological cancers
Abstract The invasion of a tumour through tissue limiting basement membranes is the critical step in malignant growth. Gelatinases (MMP-2 and MMP-9) are endopeptidases capable of degrading extracellular and pericellular matrix proteins such as collagen IV, the major component of basement membranes....
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2006
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| Online Access: | http://urn.fi/urn:isbn:951428187X http://nbn-resolving.de/urn:isbn:951428187X |