Pathophysiological and clinical consequences of the mitochondrial DNA 3243A→G mutation
Abstract This study describes clinical and biochemical consequences of the 3243A→G mutation in the tRNALeu(UUR) gene of the mitochondrial DNA. Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS syndrome) is usually caused by this mutation. Demyelinating polyneuropat...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Oulu
2000
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| Online Access: | http://urn.fi/urn:isbn:9514255380 http://nbn-resolving.de/urn:isbn:9514255380 |