Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak

Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak

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The aim of our study was to determine whether and how it changes expression and production of COX-1 and 2 in the spinal cord at different types of pain and to determine the effect of selected analgesics in the expression and production of COX-1 and COX-2 in the lumbar spinal cord in a model of infla...

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Main Author: Procházková, Michaela
Other Authors: Kršiak, Miloslav
Format: Doctoral Thesis
Language:Czech
Published: 2010
Online Access:http://www.nusl.cz/ntk/nusl-450845
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spelling ndltd-nusl.cz-oai-invenio.nusl.cz-4508452021-09-19T17:10:58Z Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak The changes in gene expression and production of cyclooxygenases in the spinal cord due to pain and drugs Procházková, Michaela Kršiak, Miloslav Farghali, Hassan Rokyta, Richard The aim of our study was to determine whether and how it changes expression and production of COX-1 and 2 in the spinal cord at different types of pain and to determine the effect of selected analgesics in the expression and production of COX-1 and COX-2 in the lumbar spinal cord in a model of inflammatory pain. All experiments were performed in the dissertation were performed in rats. Pain was measured using the plantar test and von Freys filaments. Expression of cyclooxygenase was tested using real-time PCR analysis, while the production of COX-1 and COX-2 was measured by ELISA method. 2010 info:eu-repo/semantics/doctoralThesis http://www.nusl.cz/ntk/nusl-450845 cze info:eu-repo/semantics/restrictedAccess
collection NDLTD
language Czech
format Doctoral Thesis
sources NDLTD
description The aim of our study was to determine whether and how it changes expression and production of COX-1 and 2 in the spinal cord at different types of pain and to determine the effect of selected analgesics in the expression and production of COX-1 and COX-2 in the lumbar spinal cord in a model of inflammatory pain. All experiments were performed in the dissertation were performed in rats. Pain was measured using the plantar test and von Freys filaments. Expression of cyclooxygenase was tested using real-time PCR analysis, while the production of COX-1 and COX-2 was measured by ELISA method.
author2 Kršiak, Miloslav
author_facet Kršiak, Miloslav
Procházková, Michaela
author Procházková, Michaela
spellingShingle Procházková, Michaela
Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak
author_sort Procházková, Michaela
title Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak
title_short Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak
title_full Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak
title_fullStr Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak
title_full_unstemmed Změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak
title_sort změny exprese a produkce cyklooxygenáz v míše vlivem bolesti a farmak
publishDate 2010
url http://www.nusl.cz/ntk/nusl-450845
work_keys_str_mv AT prochazkovamichaela zmenyexpreseaprodukcecyklooxygenazvmisevlivembolestiafarmak
AT prochazkovamichaela thechangesingeneexpressionandproductionofcyclooxygenasesinthespinalcordduetopainanddrugs
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