Využití optické koherentní tomografie a evokovaných zrakových potenciálů v předoperačním a pooperačním sledování pacientů s útlakem optického chiasmatu

• Main Author: Póczoš, Pavel
• Other Authors: Jirásková, Naďa
• Format: Doctoral Thesis
• Language: Czech
• Published: 2019
• Online Access: http://www.nusl.cz/ntk/nusl-398582

Use of optical coherence tomography and visual evoked potentials recording in preoperative and postoperative monitoring of patients with optic chiasm compression The objective of this prospective study is to explore the benefits of optical coherence tomography (OCT), resp. visual evoked potentials (VEP), in cases of optic chiasm (OC) compression by measuring the thickness of the retinal nerve fiber layer (RNFL) and the ganglion cell layer (GCL), resp. the implicit time and the amplitude resulting from pattern- reversal VEP (R-VEP) and motion-onset VEP (M-VEP). Material and methods: 16 patients (32 eyes) with chiasmal compression were included in the study. They presented no other pathology of the visual pathway or of the eye globe. The second inclusion criterion was a subsequent indication of decompressive surgery. Measurements of visual acuity, visual field, RNFL, GCL, R-VEP and M-VEP were performed once preoperatively and three times postoperatively (one week, 3 and 6 months postoperatively). The degree (grade 0-5) of chiasmal compression was determined on preoperative brain magnetic resonance imaging (MR). In need of some data analysis, participants were split into a group with no or minimal (grade 0-1) and with substantial pressure (grade 2-4) on OC. Results: The median global peripapillary RNFL...