Protinádorová aktivita a toxicita konjugátů na bázi HPMA kopolymerů nesoucí cytostatikum
7 ABSTRACT In this study, we addressed the biological activity and pharmacological features of selected HPMA copolymer-based drug conjugates. We determined their cytostatic activity in vitro as well as toxicity in vivo and therapeutic effcicacy in mouse tumor models. Assessment of maximum tolerate...
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Format: | Doctoral Thesis |
Language: | English |
Published: |
2018
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Online Access: | http://www.nusl.cz/ntk/nusl-380319 |